Q: structure of protein complex + alanine scan

Romano Kroemer romano at BELLATRIX.PCL.OX.AC.UK
Tue Aug 25 08:35:18 EST 1998


Dear Bioforum,

can anyone point me to references concerning the following topic:

Systematic "alanine scanning" studies on protein complexes for which the
  (wild type)structure is known (from NMR/crystal structure).

I am aware of two examples:
 human growth hormone + receptor
 anti-hen egg white lysozyme (HEL) antibody + HEL

Thank you very much for your input.

Best regards
Romano Kroemer

-- 
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Dr. Romano T. Kroemer
Phys. & Theoret. Chem. Lab.
University of Oxford
South Parks Rd.                       | Tel:     ++44-1865-275475 
Oxford OX1 3QZ                        | Fax:     ++44-1865-275410
England, U.K.                         | Email:   romano at bellatrix.pcl.ox.ac.uk
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