Solaris Thrashing after blast searches

[west999 at my-deja.com]

Hello-

I am running Solaris 8 on an Intel machine with 1gig RAM and 1 gig of
swap space.

I am running a lot of blast searches.  After running several of these
searches my machine starts thrashing.  Sometimes it gets so bad that
the machine will freeze for up to half an hour.  Even after it
unfreezes performance is very poor.

When this is happening I get various messages telling me I am out of
swap space and out of memory.

Any Suggestions?  Any virtual memory tuning I can do?

Thanks in advance...
Dan


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