[Bioforum] meaning of expression values in microarray

Nel N. (sent by Nabble.com) lists at nabble.com
Thu Jan 26 11:37:58 EST 2006


hi-i'm a modelling(math) student and are working on cancer predictions which uses biology dataset-so i dun quite hav biology knowledge-however,the dateset i'm working on which was obtained from Affymetrix chip(micrarray technology), it contained genes expressions values which include positive and negative values-i've tried searching the net for the meaning of those values but fail to get an exact answer-to what i know, the values should represent some intensity of presence of genes-if so, how come there's negative values?i mean aren't intensity values supposed to be all positive??
i hope someone can enlighten me with their microarray knowledge
thank you
God bless!
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