[Bioforum] Question: Blood (serum) clotting - Help!

[Don Shin]

Dear Laurie,

I found your post from 1998 using a Google search and was wondering 
if you ever found a resolution to your problem regarding "serum 
clots." I recently began a study in which I need to isolate serum 
(from rodents), and for reasons that are unclear, I am getting a 
thick clot (presumably fibrin) that makes it almost impossible to 
obtain a useable amount of serum. Clotting time, temperature, and 
spinning speed do not seem to affect the result.  Any suggestions 
would be greatly appreciated!

Thank you.
Don Shin