[Bioforum] GRChr37: NN..NNACGTNN...NN

Serikzhan S. Kazi via bioforum%40net.bio.net (by kazi.serikzhan from gmail.com)
Mon Sep 12 01:56:57 EST 2011


Hi all,

if you inspect 
ftp://ftp.1000genomes.ebi.ac.uk/vol1/ftp/technical/reference/human_g1k_v37.fasta.gz 
--
the build "1000GP" used in their VCF results as a reference genome,
you'll find that every chromosome starts with a run of "N"s and ends 
with a run of "N"s.
The question is: how do they know what is the length of the chromosome 
in the first place
to put specific number of leading and trailing "N"s?



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