Course Mol. Genetics, Holland, May/June 1992

Thu Feb 13 04:12:00 EST 1992

****       Advanced Course in Molecular Genetics       ****

               May 31 (6 pm) - June 5, 1992

                   Castle "Oud Poelgeest"
                   Leiden, The Netherlands

A combined theoretical and practical course, highlighting the
impact of genome research and mutation analysis on the
understanding of genetic disease and cancer. The course includes
morning lectures, afternoon demos and evening symposia and is
aimed at PhD students and postdoctoral fellows in the life

****    Symposium speakers:
A.J. Levine, D.L. Nelson, P.N. Goodfellow, A.J.M. Berns

****    Lecturers:
E. Bakker, J.T. den Dunnen, P. Devilee, R. Fodde, R.R. Frants,
A.J. van der Eb, G. Grosveld, J.H.J. Hoeijmakers, A.G. Jochemsen,
W.M. Kast, J.A. Maassen, L.G. Mullenders, C. Mummery, M.H.M.
Noteborn, G.J.B. van Ommen, B.A. Oostra, A.K. Raap, D. Valerio, A.
Westerveld, A. Zantema

****    Lecture and demo topics:

Day 1-2: Linkage analysis, positional cloning, genome mapping,
polygenic and multifactorial disease, YAC and Pulsed Field
technology, multicolor FISH cytogenetics, PCR-, DGGE- and
SSCP-applications to mutation detection.

Day 3: Hybrid cell genetics, DNA transfection and transformation
of mammalian cells, microinjection, retroviral gene therapy,
homologous recombination, transgenic animals.

Day 4-5: Fundamental and applied aspects of carcinogenesis:
Oncogenes, tumor suppressor genes, chromosome translocations and
oncogenic viruses, signal transduction, hereditary cancer
syndromes, cancer immune therapy, recombinant oncogene expression
systems and vaccine development.

****   Organizers

The course is organized by The Medical Genetics Center South-West
Netherlands (MGC) and The Institute for Biotechnology Studies
Delft-Leiden (BDL).
MGC was established by the Institutes of Cell Biology and
Clinical Genetics, Erasmus University, Rotterdam and the
Departments of Molecular Carcinogenesis, Radiation Genetics and
Chemical Mutagenesis and Human Genetics, Leiden University.

*****             Registration information               *****

Subsidized course fee dfl 2500,- (PhD students, postdocs under
30). Full course fee dfl 3500,- (senior postdocs and industrial
participants). Fee includes meals and tuition. Housing of dfl
600,- is additional. Enquiries and full applications, the latter
including a short CV, description of current research,
publications and a letter of recommendation by an established
scientist, should be sent to:

Dr. H. van Ormondt, Dept. of Molecular Carcinogenesis,
Sylvius Laboratory, Wassenaarseweg 72, 2333 AL Leiden,
The Netherlands.
E-mail: wmbormon at

For applicants from Greece, Ireland, Italy, Portugal and Spain, a
limited number of grants facilitating attendance will be made
available by the Commission of the European Communities, within
the framework of the educational section ofthe Human Genome
Analysis program. If applicable, include a request with the

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