ETHICAL, LEGAL & SOCIAL ISSUES - Call for applic. to DOE

Marvin.Stodolsky%er-04 at Marvin.Stodolsky%er-04 at
Fri Feb 26 17:17:28 EST 1993

Note in SUPPLEMENTARY INFORMATION that the preapplication 
dead line date is April 15, 1993.  Application Kits for formal
proposals will be returned with DOE/OHER responses to the 
preapplications.  Preapplications can be submitted by email
with hardcopy sent by US mail, 

preferably to:

      drell at

or alternatively to

      genome at

from the Federal Register Volume 58, Issue 30, pg 8747

Department of Energy
Office of Energy Research
Energy Research Financial Assistance Program Notice 93-13:  
       Human Genome Program - Ethical, Legal, and Social Issues
AGENCY:  Department of Energy (DOE)
ACTION:  Notice inviting grant applications.

SUMMARY:  The Office of Health and Environmental Research (OHER)
of the Office of Energy Research (ER), U.S. Department of Energy
(DOE), hereby announces its interest in receiving applications in
support of the Ethical, Legal, and Social Issues (ELSI) activities
of the Human Genome Program (HGP).  This Program is a coordinated,
multidisciplinary research effort aimed at developing creative,
innovative resources and technologies that will lead to a detailed
understanding of the human genome at the molecular level.  This
particular research notice encompasses research grants that
address ethical, legal, and social issues that may arise from the
use of information and knowledge resulting from the HGP.  The DOE
especially encourages the submission of applications to conduct
multidisciplinary, empirical research on privacy issues from the
creation, use, maintenance, and disclosure of genetic information. 
This may include (but is not limited to) issues of ownership and
control of genetic information, the protection of the privacy of
genetic information, and the role(s) of high performance computers
in information management relevant to genetic data.  Applications
should demonstrate knowledge of the relevant literature, and
should include detailed plans for the gathering and analysis of
factual information and the exploration of  issues associated with
the ethical, legal, and social implications of the  knowledge
gained from the HGP.  All applications should include, where 
appropriate, detailed discussion of human subjects protection
issues, e.g., storage of, manipulation of, and access to data. 
Where survey techniques are proposed, provisions to ensure the
inclusion of women, minorities, and potentially disabled
individuals must be described, unless specific exclusions are
scientifically necessary and justified in detail.  All proposed
research applications should address the issue of efficient
dissemination of results to the widest appropriate audience.

The DOE is also soliciting applications for the preparation and
dissemination of educational materials in any appropriate medium
that will enhance public understanding of both the scientific
aspects and the ethical, legal, and social aspects of the HGP.  In
addition, the DOE is encouraging applications for the support of
conferences focusing on specific issues or areas of concern
related to the ethical, legal, and social implications of the HGP. 
Educational and conference applications should also demonstrate
awareness of the relevant literature, and include detailed plans
for the accomplishment of project goals, including, where
appropriate, video productions.  In the case of educational
activities, the DOE strongly recommends inclusion of assessments
of effectiveness of the proposed activities.  In the case of all
conferences, a fairly detailed and complete roster of committed
speakers is necessary.  At the completion of the conference, a
summary or report is required.  Educational and conference
applications must also demonstrate   awareness of the need to
reach the widest appropriate audience. 

DATES:  Formal applications submitted in response to this notice
must be received by 4:30 p.m., E.D.T., July 15, 1993, to be
accepted for merit review  in September 1993 and to permit timely
consideration for award in Fiscal Year 1994.

ADDRESSES:  Formal applications referencing Program Notice 93-13
should be forwarded to:  U.S. Department of Energy, Acquisition
and Assistance Management Division, ER-64, Washington, D.C. 
20585, ATTN:  Program Notice  93-13.  The following address must
be used when submitting applications by U.S. Postal Service
Express Mail or any commercial mail delivery service, or when
handcarried by the applicant:  U.S. Department of Energy,
Acquisition and Assistance Management Division, ER-64, 19901
Germantown Road, Germantown, MD  20874.

Health and Environmental Research, ER-72 (GTN), Office of Energy
Research, U. S. Department of Energy, Washington, D.C., 20585,
(301) 903-6488.

SUPPLEMENTARY INFORMATION:  Potential applicants are strongly
encouraged to submit a preapplication in accordance with 10 CFR
600.10(d)(2), which consists of two to three pages of narrative
describing research objectives, methods of accomplishment, and
measures of accomplishment including anticipated products.  These
will be reviewed relative to the scope and the research needs of
the DOE's Human Genome Program ELSI activities.  Preapplications
referencing Program Notice 93-13 should be received by April 15,
1993, and sent to Dr. Daniel W. Drell, Office of Health and
Environmental Research, ER-72 (GTN), U.S. Department of Energy,
Washington, D.C. 20585.  Telephone and FAX numbers are required
parts of the preapplication.  A response to the preapplication 
discussing the potential program relevance of a formal application
will be communicated by within 30 days of receipt.

The dissemination of materials and research data in a timely
manner is essential for progress towards the goals of the DOE
Human Genome Program.  The OHER requires the timely sharing of
resources and data.  Applicants should, in their applications,
discuss their plans for disseminating research data and
information, educational and training materials, and conference
and meeting results.  Funds to defray the costs of disseminating
materials and results are allowable; however, such requests must
be adequately justified.  It is anticipated that approximately
$900,000 will be available for grant awards during FY 1994,
contingent upon availability of appropriated funds.  Multiple year
funding of grant awards is also contingent upon availability of
funds.  Previous awards have ranged from $5,000 per year to
$400,000 per year with terms from 1 to 3 years.  Similar award
sizes are anticipated for new grants.  Information about
development and submission of applications, eligibility,
limitations, evaluation, selection process, and other policies and
procedures may be found in the ER Special Research Grants
Application Kit and Guide and 10 CFR Part 605.  The application
kit and guide is available from the U.S. Department of Energy,
Office of Health and Environmental Research, Office of Energy
Research, ER-72, Washington, D.C. 20585.  Telephone requests may
be made by calling (301) 903-6488.  The Catalog of Federal
Domestic Assistance number for this program is 81.049.

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