human chromosome mapping panels available

Jeanne Beck jbeck at UMDNJ.EDU
Wed Aug 24 14:54:36 EST 1994


HUMAN/RODENT SOMATIC CELL HYBRID
 MAPPING PANELS

The National Institute of General Medical Sciences' (NIGMS) Human 
Genetic Mutant Cell Repository has mapping panels available for 
distribution as cell cultures or DNA. Regional mapping panels, consisting 
of human/rodent somatic cell hybrids with deletion or derivative human 
chromosomes, are currently available for human chromosomes 4, 5, 11, 
15, 17, and 18. Regional mapping panels for other human chromosomes 
will be available in the near future. In addition, a new version of mapping 
panel #2 is now available. Version 2 consists of 24 human-rodent somatic 
cell hybrids each retaining a single intact human chromosome. In Version 
2, the original hybrids retaining human chromosomes 1 and 20 have been 
replaced. The new monochromosomal hybrid for chromosome 1, 
GM/NA13139, is a human/mouse hybrid in which 96% of the cells retain 
the human chromosome and the monochromosomal hybrid for 
chromosome 20, GM/NA13140, is a human/mouse hybrid in which 68% of 
the cells retain the human chromosome. All panels have been characterized 
at a minimum by (1) G-banded chromosome analysis, (2) in situ 
hybridization using biotinylated total human DNA, and (3) Southern blot 
hybridization. For information or a Repository catalog, contact the NIGMS 
Human Genetic Mutant Cell Repository, Coriell Cell Repositories, Coriell 
Institute for Medical Research, 401 Haddon Avenue, Camden, NJ 08103; 
phone (800) 752-3805 in the United States, (609) 757-4848 from other 
countries; FAX (609) 757-9737. 

-- 
Jeanne C. Beck                                      Internet: jbeck at umdnj.edu
Coriell Cell Repositories                              Voice: 609-757-4847
Coriell Institute for Medical Research                   Fax: 609-757-9737



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