[This is a follow up to the DOE Genome Informatics Announcement (by David
Galas) 11 August 1993, on the bio.net channels, and the November '93 issue
of Human Genome News.]
* * * A N N O U N C E M E N T * * *
DOE Expands Sequence Data Management Activities
Support of Genome and Structural Biology Research
The Office of Health and Environmental Research of the U.S. Department of
Energy (DOE) is pleased to announce the continuation and further
development of the pioneering sequence database activities of the Los
Alamos National Laboratory (LANL). All sequence data management activities
at LANL are now operating as an independent database with an expanded
mission and a new name: the Genome Sequence DataBase (GSDB).
The GSDB is accepting new data submissions and is also providing update and
annotation services for existing data. Through reciprocal data exchange,
all data submitted to the GSDB will also appear in the DNA Databank of
Japan, the EMBL Data Library, and GenBank.
The email addresses for the Genome Sequence DataBase are:
datasubs at t10.lanl.gov - for data submissions
update at t10.lanl.gov - for updates/corrections to existing data
offsite at t10.lanl.gov - for information on our offsite user program
Confirmation of receipt of GSDB submissions are usually issued within a few
hours. Accession numbers are normally issued within 24 hours of receipt of
a submission. Submission processing is normally complete within an
additional 24 hours (for a total of two working days). At that time
submitters will receive a copy of the resulting entries for review.
Non-confidential entries will be promptly forwarded on to the other DNA
sequence databases for inclusion in their data collections.
For further information, see the announcement in the Human Genome News
November 1993;5(4):4). Newsletters are archived on gopher.gdb.org under
Genome Project/Human Genome News or contact:
The Genome Sequence DataBase Staff
Los Alamos National Laboratory
Los Alamos, NM 87545 USA
NOTE: Sequence data may also be sent to:
DDBJ DNA Data Bank of Japan
EMBL European Molecular Biology Laboratory
NCBI National Center for Biotechnology Information
These three sites share data with each other and with LANL so that all data
rapidly appear in all databases, regardless of the site to which the data
are submitted. Thus, data sent to any of the sites will be entered into
the DNA Data Bank of Japan (DDBJ), the EMBL Data Library (EMBL), the
Genome Sequence DataBase (LANL), and GenBank (NCBI).
New data submissions may be sent to these three sites at the following
DDBJ ddbjsub at ddbj.nig.ac.jp
EMBL datasubs at embl-heidelberg.de
NCBI gb-sub at ncbi.nlm.nih.gov
Corrections/additions to existing entries may be sent to any of:
DDBJ ddbjupdt at ddbj.nig.ac.jp
EMBL update at embl-heidelberg.de
NCBI update at ncbi.nlm.nih.gov
BACKGROUND: Historical Role of Los Alamos
In the 1970's, Walter Goad established the Los Alamos Sequence Database, a
pioneering effort at LANL that in 1982 evolved into the GenBank project.
The LANL continued to expand and build the database in collaboration with
the firm Bolt, Beranek, and Newman under funding provided by NIGMS and
other Federal agencies. In 1987, the LANL continued to be the site of
database design and maintenance, working with IntelliGenetics.
In 1992, NIH transferred its management control for the GenBank project
from NIGMS to NCBI at the National Library of Medicine. At that time, DOE
and NCBI entered into an Inter-Agency Agreement (IAA) so that LANL could
provide assistance in processing direct submissions for NCBI. The IAA
noted, "For nine years, LANL has been responsible for the design and
management of gene sequence data as part of the GenBank project. . . . In
the most recent re-competition, all three proposals that were in the
competitive range included LANL as a subcontract for the direct data
submission component of the project. Thus, LANL was recognized not only
for its past experience in establishing the procedures for collecting and
managing biological data, but for its innovative approaches in handling
data prior to or independent of the publication process."
Now, NCBI has developed its own capacity for processing direct submissions,
freeing LANL to develop new approaches, tools, and services targeted
specifically for the genome community.