DOE Genome Informatics -- Announcement II

John.Wooley at mailgw.er.doe.gov John.Wooley at mailgw.er.doe.gov
Fri Jan 7 22:27:26 EST 1994


  [This is a follow up to the DOE Genome Informatics Announcement (by David
  Galas) 11 August 1993, on the bio.net channels, and the November '93 issue
  of Human Genome News.]


                    * * *   A N N O U N C E M E N T   * * *


                DOE Expands Sequence Data Management Activities

                                      in

               Support of Genome and Structural Biology Research



  The Office of Health and Environmental Research of the U.S. Department of
  Energy (DOE) is pleased to announce the continuation and further
  development of the pioneering sequence database activities of the Los
  Alamos National Laboratory (LANL).  All sequence data management activities
  at LANL are now operating as an independent database with an expanded
  mission and a new name: the Genome Sequence DataBase (GSDB).

  The GSDB is accepting new data submissions and is also providing update and
  annotation services for existing data.  Through reciprocal data exchange,
  all data submitted to the GSDB will also appear in the DNA Databank of
  Japan, the EMBL Data Library, and GenBank.

  The email addresses for the Genome Sequence DataBase are:

      datasubs at t10.lanl.gov - for data submissions
      update at t10.lanl.gov   - for updates/corrections to existing data
      offsite at t10.lanl.gov  - for information on our offsite user program

  Confirmation of receipt of GSDB submissions are usually issued within a few
  hours.  Accession numbers are normally issued within 24 hours of receipt of
  a submission.  Submission processing is normally complete within an
  additional 24 hours (for a total of two working days).  At that time
  submitters will receive a copy of the resulting entries for review. 
  Non-confidential entries will be promptly forwarded on to the other DNA
  sequence databases for inclusion in their data collections.

  For further information, see the announcement in the Human Genome News
  November 1993;5(4):4).  Newsletters are archived on gopher.gdb.org under
  Genome Project/Human Genome News or contact:

      The Genome Sequence DataBase Staff
      Group T-10
      Los Alamos National Laboratory
      Los Alamos, NM 87545  USA
      (505) 665-2177



  NOTE:  Sequence data may also be sent to:

     DDBJ    DNA Data Bank of Japan
     EMBL    European Molecular Biology Laboratory
     NCBI    National Center for Biotechnology Information

  These three sites share data with each other and with LANL so that all data
  rapidly appear in all databases, regardless of the site to which the data
  are submitted.  Thus, data sent to any of the sites will be entered into
  the DNA Data Bank of Japan (DDBJ), the EMBL Data Library (EMBL), the
  Genome Sequence DataBase (LANL), and GenBank (NCBI).

  New data submissions may be sent to these three sites at the following
  addresses :

     DDBJ    ddbjsub at ddbj.nig.ac.jp
     EMBL    datasubs at embl-heidelberg.de
     NCBI    gb-sub at ncbi.nlm.nih.gov

  Corrections/additions to existing entries may be sent to any of:

     DDBJ    ddbjupdt at ddbj.nig.ac.jp
     EMBL    update at embl-heidelberg.de
     NCBI    update at ncbi.nlm.nih.gov


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  BACKGROUND:  Historical Role of Los Alamos

  In the 1970's, Walter Goad established the Los Alamos Sequence Database, a
  pioneering effort at LANL that in 1982 evolved into the GenBank project. 
  The LANL continued to expand and build the database in collaboration with
  the firm Bolt, Beranek, and Newman under funding provided by NIGMS and
  other Federal agencies.  In 1987, the LANL continued to be the site of
  database design and maintenance, working with IntelliGenetics.

  In 1992, NIH transferred its management control for the GenBank project
  from NIGMS to NCBI at the National Library of Medicine.  At that time, DOE
  and NCBI entered into an Inter-Agency Agreement (IAA) so that LANL could
  provide assistance in processing direct submissions for NCBI.  The IAA
  noted, "For nine years, LANL has been responsible for the design and
  management of gene sequence data as part of the GenBank project. . . .  In
  the most recent re-competition, all three proposals that were in the
  competitive range included LANL as a subcontract for the direct data
  submission component of the project.  Thus, LANL was recognized not only
  for its past experience in establishing the procedures for collecting and
  managing biological data, but for its innovative approaches in handling
  data prior to or independent of the publication process."

  Now, NCBI has developed its own capacity for processing direct submissions,
  freeing LANL to develop new approaches, tools, and services targeted
  specifically for the genome community.



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