Announcing release 8 of the Whitehead/MIT MOUSE GENETIC MAP

Ert Dredge ert at karlo.wi.mit.edu
Sat Nov 5 12:23:02 EST 1994


            ANNOUNCING THE EIGHTH RELEASE OF THE WHITEHEAD
         INSTITUTE/MIT GENOME CENTER GENETIC MAP OF THE MOUSE

Release eight of the Whitehead Institute/MIT Genome Center Genetic Map
of the Mouse is now available.  This map consists of randomly-chosen
simple sequence length polymorphisms (microsatellites) that can be
analyzed using the polymerase chain reaction, as described in Dietrich,
W., et. al., Genetics 131:423-447 (1992), and most recently in Dietrich,
W.F. et al., Nature Genetics 7:220-245 (1994)

Currently the released map contains 5250 markers.  The markers fall into
20 linkage groups spanning approximately 1400 cM with an average spacing
of approximately 0.3 cM.

This data can be obtained in three different ways:

1.  Via internet e-mail using a database e-mail server. Using this
service you can obtain locus and assay names of mapped SSLPs, the
forward and reverse primer sequences, the genotypes of the loci on the
mapping cross, the sizes of the PCR products on selected standard inbred
strains, and other useful information.  The database can be queried for
markers meeting a number of different criteria.  For example, you can
ask for markers by name, by chromosome, or by position on the map.  You
can even request a list of markers that are polymorphic between two
mouse strains.

2.  Via anonymous ftp to genome.wi.mit.edu.  Log in as "anonymous" and
use your e-mail address as password.  The release can be found in the
directory /distribution/mouse_sslp_release/oct94/.  The file "README"
describes the file formats and gives other information about the map.

3.  Via a "World-Wide Web" browser.  Point your WWW client (e.g., NCSA
Mosaic) at "http://www-genome.wi.mit.edu/".

To obtain copies of the most current e-mail query forms, send a message
to "genome_database at genome.wi.mit.edu" with either a subject line or
body text of "help". You will receive instructions and a query form by
return mail.  Just fill out the form, send it to
"genome_database at genome.wi.mit.edu", and the answer to your query will
be mailed back automatically.

This project is an ongoing one.  As new markers are added to the map
they will be released on a quarterly basis on the following schedule:

January 1995
April 1995

These data releases do not constitute scientific publication of CGR's
work, but rather provides scientists with a regular look into our lab
notebooks.  For projects aimed at the analysis of particular genes or
subchromosomal regions, the Whitehead/MIT CGR grants permission to use
our data without the need for a formal collaboration, subject only to
appropriate acknowledgment.  For projects aimed at large-scale mapping
of entire chromosomes or entire genomes, use of the data and markers
should be on a collaborative basis.  Please see the aforementioned
README file or contact CGR directly.

Please address questions and comments to me at the address below.  See
the README file for news of the newest member of the Dietrich family.

- Ert Dredge

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Ert Dredge <ert at genome.wi.mit.edu>                     Mondays 8:30pm - 10:30pm
Whitehead Institute's Center for Genome Research        WMBR 88.1 FM, Cambridge
One Kendall Sq, Cambridge, Bldg 300, 5th floor, 02139        Requests: 253-8810
617-252-1922 (w), 617-252-1902 (fax)                 Beauty Canadian tunes, eh?
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