CALL FOR VOTES: RECOMBINATION/bionet.molbio.recombination

BIOSCI Administrator biosci-help at net.bio.net
Mon Aug 28 14:39:52 EST 1995


Voting is now open on the following proposal to create the mailing
list & newsgroup

RECOMBINATION/bionet.molbio.recombination

The charter was not modified as a result of the discussion.

*** NOTE *** We are often running several votes for other newsgroups,
so please be certain to follow the voting directions *carefully*!  If
you just send in a message saying "YES" or "NO" it will not be counted
if it is not clear which proposal you are responding to.

----------------------------------------------------------------------
Proposal to establish RECOMBINATION/bionet.molbio.recombination

Proposed USENET name:           bionet.molbio.recombination  (unmoderated)

Proposed mailing list name:     RECOMBINATION

Proposed e-mail addresses:      recom at net.bio.net
                                recom at daresbury.ac.uk

Discussion leaders:

*Note: Area of expertise is written in brackets

Graham Dellaire,  e-mail: popa0206 at po-box.mcgill.ca (b2xe at musicb.mcgill.ca)
Department of Medicine (Div. of Exp. Medicine)
McGill Univeristy,
Montreal, Quebec, Canada 
*(Genome Accessibility, Line-1 sequences, Gene Conversion and Ectopic Int.)


George Szatmari,  e-mail: szat at ere.umontreal.ca
Assistant Professor
Departement de Microbiologie et Immunologie
Universite de Montreal
CP 6128 Succursale Centre-Ville
Montreal, Quebec H3C 3J7
phone (514)343 5767  fax (514)343 5701
*(Site Specific Recombination Sytems)


Terry Chow e-mail: MDTY at musica.mcgill.ca
Associate Professor
Department of Oncology
Division of Radiation-Oncology
McGill University
Montreal General Hospital
1650 Ave. Cedar
Montreal, Quebec H3G 1A4
phone (514)934 8040 ext. 4179
fax (514)934 8220
*(Mammalian Genetics/gene therapy)


Dana Lasko e-mail: CZDL at musica.mcgill.ca
Assistant Professor of Medicine and Human Genetics
Project Director
Terry Fox Molecular Oncology Group
Lady Davis Institute for Medical Research
3755 Cote-Ste-Catherine Rd.
Montreal, PQ
Phone 340-8260 ext. 3454 (office and machine) or  ext. 5251 (lab)
Fax 340-7502
*(Replication and Recombination)



Charter:

The purpose of the RECOMBINATION newsgroup is to provide a proper
forum for the discussion of issues pertaining and involving recombination 
of DNA or RNA, in its many forms (see _Topics of Discussion_).  Primarily 
it should enable those researchers who work in recombination or aligned 
fields to communicate ideas and information, as well as, provide a chance 
for
collaboration among national and international research groups.


Topics of Discussion include:
1. Gene conversion and ectopic integration 
2. Genome accessibility and nuclear/chromosome structure and recombination
                    -Matrix attachment sites (MARS)
                    -nucleosomes, histone 1 
                    -recombination hotspots
                    -fragile sites 
                    -origins of replication
3. Effect of DNA topology on recombination (Triple strand, Z-DNA, cruciform, 
bent etc)
4. Homologous recombination vs. nonhomologous or illegitimate 
                    -comparisons between bacterial, yeast and higher 
eukaryotic recombination
                     systems (ex. fungi, mammals) 
5. Models of recombination (One-end invasion, Double strand Break Repair, 
SSA etc)
6. Site-specific recombination systems (invertase, Cre and Flp recombinase 
etc)
7. Specific recombination systems in complex organisms
                    -VDJ recombination
                    -Antigenic variation and recombination (ex. 
trypanosomes, HIV, N.gonorrhea) 
                    -Yeast mating type locus 
8. Transcription and recombination 
9. DNA replication and recombination (ex. gene amplification (DHFR etc))
10. Evolution of the Genome
                    -retroposons (Line-1, Sine's), retroviruses and 
transposons
                    -formation of gene clusters and comparative mapping
                    -recombination between other repeat elements (alpha 
satellites, telomeres)
11. DNA repair systems and recombination (DSB and mismatch repair)
                    -including DNA repair deficient diseases (ex. Xoderma 
Pigmentosum)
12. Applications of recombination
                    -Gene therapy
                    -Transgenics and gene transfer
13. Viral diversity through RNA recombination
14. Population genetics and recombination:i.e. as a source of allelic 
variation
and as a measure of genetic exchange within and between populations.

In addition this newsgroup provides:

        A forum for the exchange of information about future congresses
        and meetings in areas of molecular biology relating to recombination

        A forum for the exchange of information about textbooks, internet
        resources, visual materials, and computer programs.

        A source of quick help for last-minute troubleshooting, sources of 
materials,
        and practical advice; in areas such as
                     -Vector design for transgene experiments
                     -Gene transfer techniques
                     -Animal models and cell lines
                     -Gene therapy protocols 


Subscribers are welcome.  Contributions within the functions outlined
above are encouraged.

The newsgroup is -UNMODERATED-.
----------------------------------------------------------------------

Voting is now open on the proposal for
RECOMBINATION/bionet.molbio.recombination and will run through 24:00
hrs Pacific Time on 26 September 1995.  Please send your vote to
either of the following addresses:

Address                               Location        Network
-------                               --------        -------
biovote at daresbury.ac.uk               U.K.            JANET
biovote at net.bio.net                   U.S.A.          Internet/BITNET

PLEASE BE SURE TO FOLLOW THE FORMAT BELOW - WE OFTEN RUN MORE THAN ONE
VOTE AT A TIME SO A SIMPLE "YES" OR "NO" MESSAGE WITHOUT THE NEWSGROUP
NAME MAY BE AMBIGUOUS.  Your vote should contain a single line:

YES on RECOM

if you favor allowing the creation of this newsgroup or

NO on RECOM

if you think that this proposal will adversely affect the
BIOSCI/bionet system.  While not intended to be an exhaustive list of
possible concerns (more specific concerns may have been raised during
the discussion period on BIOFORUM/bionet.general and interested
readers are referred to these), some general reasons for voting NO
might be if you are concerned about newsgroup proliferation and/or
believe that the proposed group will not be utilized, or if you think
that the proposed newsgroup would substantially duplicate or overlap
with the function of existing newsgroups.  If you are simply not
interested in participating in the newsgroup above, please don't cast
a NO vote, but instead just don't vote at all.

The newsgroup proposal must receive at least 80 YES votes to pass and
the number of YES votes must be greater than the number of NO votes by
at least 40.  Discussion of the newsgroup proposal is now closed and
we strongly discourage posting any messages in other forums about the
fact that a CALL FOR VOTES has been issued.

				Sincerely,

				Dave Kristofferson
				BIOSCI/bionet Manager

				biosci-help at net.bio.net



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