Announcing PROMOTER SCAN 1.50 release

Dan S. Prestridge, Ph.D. danp at biosci.cbs.umn.edu
Wed Nov 8 00:42:01 EST 1995


ANNOUNCING THE AVAILABILITY OF PROMOTER SCAN version 1.50 for UNIX:

PROMOTER SCAN Version 1.50 for UNIX is now available. The program for
IBM PCs is NOT YET READY, and will be announced at a later date.
Improvements in version 1.50 (over version 1.00) are:

1) The correction of the over-prediction of TATA boxes (a bug reported
   by Dr. James Fickett at Los Alamos National Lab).

2) An 2/3rds reduction in the number of false positives reported by
   the program. Previously PROMOTER SCAN reported one false positive
   in about 5600 bases; PROMOTER SCAN version 1.5 reports about one
   false positive in 17,200 bases (while recognizing about 70% of
   promoter sequences).

If you are interested in getting a copy of the program, send E-mail to
danp at biosci.cbs.umn.edu for instructions.

PROMOTER SCAN is designed to find putative eukaryotic Pol II promoter
sequences in primary DNA sequence data. This program is experimental
in
nature, and should be used as an experimental tool.  PROMOTER SCAN is
best used to locate regions in primary DNA sequence that might be good
candidate regions to further test for promoter functionality. At this
time, based upon test promoter and non-promoter sequence sets, the
program recognizes approximately 70% of all EPD primate promoter
sequences, with a false positive rate of about one in every 17,200
bases.

Please refer to:

Prestridge, D.S. (1995). Predicting Pol II Promoter Sequences Using
Transcription Factor Binding Sites. J Mol Biol 249(5):923-932.

If you have any additional questions, please let me know.

When requesting further information on how to obtain PROMOTER SCAN,
PLEASE SPECIFY UNIX OR IBM PC.

			Sincerely,

				Dan S. Prestridge
___________________________________________________________________________
Dan S. Prestridge, Ph.D.                        E-mail:
DANP at BIOSCI.UMN.EDU
Director                                        Telephone: (612)
625-3744
Advanced Biosciences Computing Center           Fax: (612) 625-5780
University of Minnesota
1479 Gortner Ave.
St. Paul,  MN  55108
___________________________________________________________________________





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