New Release 1.1 - ProClass Protein Family Database and ProQuery Program
wu at uthct.edu
wu at uthct.edu
Tue Jul 1 13:26:49 EST 1997
The Bioinformatics Research Group of the University of Texas Health Center at
Tyler is pleased to announce Release 1.1 of its ProClass Protein Family
Database and ProQuery ProClass Query Program. The database is available for
on-line search at:
Free copies of the ProClass Database and ProQuery Program can be obtained via
anonymous FTP to:
The ProClass Protein Family Database is a non-redundant database organized
according to family relationships as defined collectively by PIR superfamilies
and ProSite patterns. The objectives are to facilitate protein family
information retrieval, unveil domain and family relationships, and classify
multi-domained proteins. This is achieved by combining global and motif
sequence similarities into a single classification scheme. The current
ProClass release consists of 91,319 sequence entries retrieved from
PIR-international (Release 52.0, March 1997) and SwissProt (Release 34.0,
November 1996) databases.
Major new features of ProClass Release 1.1 are:
- Query program distribution: Newly available is the ProQuery program with
which one can query ProClass database for record retrieval using various
search keys. The program can be installed on UNIX machines for use in
batch-mode or via WWW interface.
- New links: Hypertext links to PIR_ALN superfamily/domain multiple sequence
alignments, PIR superfamily memberships, and ProDom protein domain database
are provided in this release, in addition to links to SwissProt, ProSite
and PIR databases.
- New family members: Also provided is a list of family members which were
not catalogued in ProSite (Release 13.0) or PIR (Release 51.0) but
identified by our GeneFIND family identification system
Please cite the following reference in publications that benefit from the
Wu, C. H., Zhao, S. and Chen, H. L. (1996). A protein class database
organized with ProSite protein groups and PIR superfamilies. Journal
of Computational Biology, 3(4), 547-561.
If you have any questions or comments, please contact me at wu at uthct.edu.
Cathy Wu, Ph.D.
Associate Professor of Biomathematics
University of Texas Health Center at Tyler
P. O. Box 2003, Tyler, TX 75710
E-Mail : wu at uthct.edu
Fax : (903) 877-5914
Phone : (903) 877-7962
More information about the Bionews