BLAST Server at NCGR

Janine Sieja Hagerman jsh at ncgr.org
Thu Oct 15 12:53:16 EST 1998


The National Center for Genome Resources is pleased to announce the
availability
of BLAST (Basic Local Alignment Search Tool) starting today (Oct. 15).
Coming soon, the Center will also offer other powerful similarity search
methods, including
Smith-Waterman.  Please visit http://seqsim.ncgr.org to conduct free searches
and analysis.

NCGR's recent acquisition of two specialized DeCypher ES-1920 servers,
produced
by TimeLogic Corp., allows us to offer these computationally intensive search
algorithms.  The Center is the first to offer a free, publicly accessible
DeCypher server linked to a public sequence database, our Genome Sequence
DataBase (GSDB).

GSDB contains additional data, unique data sets and annotation not found in
other public databases.  This breadth of genomic data, combined with the power
to analyze data and free access, represents a formidable resource.

Nowhere else can users benefit from the combination of comprehensive data
access
and cutting-edge analysis tools.  The DeCypher servers perform a variety of
algorithms; in addition to BLAST, NCGR will provide Smith-Waterman, Frame
Search, Symmetric Frame Independent, Profile Search in early 1999; and
ClustalW
by the end of 1998.

To support flexibility in similarity searching, NCGR provides searchable
subsets
of its databases.  You may customize your target set by selecting a single or
multiple subsets.  NCGR is unique among public sequence databases in offering
this extremely useful feature.  Individual search sets are based mainly on the
taxonomic hierarchy but also include sequence tagged sites (STSs), expressed
sequence tags (ESTs) and individual human chromosomes.

NCGR is grateful to TimeLogic for its support in this effort, particularly
TimeLogics contribution of one server for use by researchers.

Please contact ncgr at ncgr.org if you have questions.

Regards,

Michael M. Harpold, Ph.D.
Chief Scientific Officer






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