ANNOUNCE: HOBACGEN release 5 availability

[Guy Perriere]

                      HOBACGEN Release 5 (July 1999)


     The  new  release  of  HOBACGEN  (the Homologous Bacterial Genes
     Database)  is  now available. Information on the database can be
     accessed at:

            http://pbil.univ-lyon1.fr/databases/hobacgen.html

     HOBACGEN  is  a  database  system  that contains all the protein
     sequences of bacteria  organized into families. It allows one to
     select  sets  of  homologous genes from bacterial species and to
     visualize  multiple  alignments  and  phylogenetic  trees.  Thus
     HOBACGEN is particularly useful for comparative genomics, phylo-
     geny and molecular evolution studies on bacteria.

     The  database contains all sequences of bacteria (eubacteria and
     archeae)  and  yeast  taken  from SWISS-PROT + TrEMBL, with some
     annotation modifications. It contains also all the corresponding
     nucleotide  sequences  from  EMBL. Homologous proteins are clas-
     sified  into  families  and multiple alignments and phylogenetic
     trees are computed for each family.

     This new version of HOBACGEN has been built using sequences from
     SWISS-PROT  37  (+ updates)  and  TrEMBL  10.  Among the 102,369
     proteins used to build this release, 82,464 are from eubacteria,
     13,021 from archaea, and 6,883 from yeast.

     If  you  use  HOBACGEN  in  a  published  work,  please cite the
     following reference:

     Perriere,  G.,  Duret, L. and Gouy, M. (1999) HOBACGEN: database
     system for comparative genomics in bacteria. submitted to Genome
     Research.



                  Guy Perriere and Laurent Duret
                  Laboratoire de Biometrie et Biologie
                  Evolutive - UMR CNRS 5558
                  Universite Claude Bernard - Lyon 1
                  43, bd. du 11 Novembre 1918
                  69622 Villeurbanne Cedex
                  France

                  Email: {perriere, duret}@biomserv.univ-lyon1.fr