Release 64.00, PIR Protein Sequence Database

pirmail pirmail at NBRF.Georgetown.Edu
Thu Apr 13 10:31:24 EST 2000


==============================================================
  ANNOUNCING RELEASE 64 OF THE PIR PROTEIN SEQUENCE DATABASE
                           and
    NEW FEATURES AND ANALYSIS TOOLS ON THE PIR WEB SITE

                http://pir.georgetown.edu/
==============================================================
RELEASE 64.00 OF THE PIR-PSD
   - Contains 178,050 entries and is available by ftp at
   - ftp://nbrfa.georgetown.edu/pir and
   - ftp://nbrf.georgetown.edu/pir

PIR-PSD ENTRIES ON THE WEB SITE HAVE COMPLETE LINKS TO:
   - KEGG, BRENDA, and metabolic pathways and enzyme databases
   - The Protein Databank of Protein Structures (PDB)
   - Clusters of Orthologous Groups (COGs) at NCBI

NEW PROTEIN SEARCH AND ANALYSIS TOOLS ON THE WEB INCLUDE:
(see Bioinformatics 16, 2000)

1. Domain Search
Searches for sequence similarity with domains annotated by
PIR-International.
The results are presented in a table and graphical bars format.

2. Global and Domain Search
Simultaneously searches the PIR-PSD and the PIR Domain Databases.
Results are presented in table and graphical format.

3. Integrated Environment for Sequence Analysis (IESA)
This program provides an integrated environment for protein sequence
analysis
using all the tools on the Web Site. You can:
- Browse PIR-International Protein Sequence Database.
- Display database statistics in graph and table format.
- Display annotations in a table format.
- Find Links to PDB, COG, KEGG, BRENDA, WIT and PIR-ASDB.
- Search text fields.
- Search specialized genomes, e.g. Homo sapiens, Mus musculus,
  S. cerevisiae and E. coli.
- Use the integrated sequence analysis tool including:
      - BLAST and FASTA searches,
      - Pattern Matching,
      - Domain Search
      - Global and Domain Search
 - Multiple alignments with feature display.
 - Annotation Similarity Search

NEW PROTEIN DATABASE AVAILABLE:

The PIR Annotation And Similarity Database (PIR-ASDB):
This is a precompiled database of FASTA scores and alignments for the
entire PIR-International
Protein Sequence Database and includes both annotation and
classification information.
The database is accessible directly, or from within the PIR Integrated
Environment for
Sequence Analysis (IESA).







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