HOBACGEN Release 8

[Guy Perriere]

                    HOBACGEN Release 8 (October 2000)


     The  new  release  of  HOBACGEN  (the Homologous Bacterial Genes
     Database)  is  now available. Information on the database can be
     accessed at:

            http://pbil.univ-lyon1.fr/databases/hobacgen.html

     HOBACGEN  is  a  database  system  that contains all the protein
     sequences  of prokaryotes organized into families. It allows one
     to  select sets of homologous genes from prokaryotic species and
     to visualize multiple alignments and phylogenetic trees.

     The  database  contains  all  sequences of bacteria, archaea and
     yeast  taken  from  SWISS-PROT,  TrEMBL and TrEMBLNEW, with some
     annotation modifications. It contains also all the corresponding
     nucleotide  sequences  from  EMBL. Homologous proteins are clas-
     sified  into  families  and multiple alignments and phylogenetic
     trees are computed for each family.

     This new version of HOBACGEN has been built using sequences from
     SWISS-PROT  39  (+  updates  until  September 29) and TrEMBL 14.
     Among  the  154,132 proteins used to build this release, 131,917
     are from bacteria, 15,389 from archaea, and 6,826 from yeast.

     If  you  use  HOBACGEN  in  a  published  work,  please cite the
     following reference:

     Perriere,  G.,  Duret, L. and Gouy, M. (2000) HOBACGEN: database
     system  for  comparative  genomics in bacteria. Genome Res., 10,
     379-385.



                  Guy Perriere and Laurent Duret
                  Laboratoire de Biometrie et Biologie
                  Evolutive - UMR CNRS 5558
                  Universite Claude Bernard - Lyon 1
                  43, bd. du 11 Novembre 1918
                  69622 Villeurbanne Cedex
                  France

                  Email: perriere at biomserv.univ-lyon1.fr