UniProt Release 4.0 Note

Amar Kalelkar ak297 at georgetown.edu
Sun Feb 20 13:55:33 EST 2005


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UniProt Release 4.0 Note
1-February-2005
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CONTENTS
1. Introduction
2. Database description
3. Current release contents
4. Description of changes made to UniProt since release 1.0
5. Forthcoming changes
6. How to link to UniProt
7. Feedback
8. Acknowledgements
9. Terms of use
10. Citation
11. Contact

1. INTRODUCTION
The UniProt Consortium--European Bioinformatics Institute (EBI), Swiss 
Institute of Bioinformatics (SIB) and Protein Information Resource 
(PIR)--is pleased to announce UniProt Release 4.0 (1-February-2005). 
UniProt is updated bi-weekly, and can be accessed online for searches or 
download at http://www.uniprot.org.

2. DATABASE DESCRIPTION
UniProt is a centralized resource for protein sequences and functional 
information. UniProt was created by joining together the information 
from Swiss-Prot, TrEMBL and PIR. UniProt is comprised of three 
components, each optimized for different uses: a) UniProt Knowledgebase 
(UniProt), b) UniProt Non-redundant Reference databases (UniRef), and c) 
UniProt Archive (UniParc). Additional information on UniProt is 
available at http://www.uniprot.org/database/DBDescription.shtml and in 
the UniProt Knowledgebase user manual 
(http://expasy.org/sprot/userman.html).

3. CURRENT RELEASE CONTENTS
-------------------------------------------------------------
UniProt Release 4.0
-------------------------------------------------------------
Database -- Entries
-------------------------------------------------------------
UniProt -- 1,757,967 (UniProt/Swiss-Prot: 168,297; UniProt/TrEMBL: 
1,589,670)
UniRef100 -- 2,114,535
UniRef90 -- 1,355,683
UniRef50 -- 729,983
UniParc -- 4,939,542
-------------------------------------------------------------

4. DESCRIPTION OF CHANGES MADE TO UNIPROT SINCE RELEASE 3.0
UniProt Knowledgebase - Please read the UniProt/Swiss-Prot and 
UniProt/TrEMBL release notes (http://expasy.org/sprot/relnotes/) and the 
recent changes document (http://expasy.org/sprot/relnotes/sp_news.html).

5. FORTHCOMING CHANGES
Forthcoming changes are described in 
http://expasy.org/sprot/relnotes/sp_soon.html.

6. HOW TO LINK TO UNIPROT ENTRIES
A detailed description of how to link to UniProt entries can be found at 
http://www.uniprot.org/support/docs/linkUniProt.html

7. FEEDBACK
We are constantly trying to improve our database in terms of accuracy 
and representation and hence consider your feedback extremely valuable. 
Please contact us if you have any questions 
(http://www.uniprot.org/support/helpdesk.shtml) or comments 
(http://www.uniprot.org/support/feedback.shtml). You can also subscribe 
to e-mail alerts (http://www.uniprot.org/support/alerts.shtml) for the 
latest information on UniProt databases.
Submit new sequence data, updates and corrections at 
http://www.uniprot.org/support/submissions.shtml

8. ACKNOWLEDGEMENTS
UniProt is supported mainly by the National Institutes of Health (NIH) 
grant U01 HG02712. Minor support for the EBI’s involvement in UniProt 
comes from the European Union contracts BioBabel (QLRT-2000-00981) and 
TEMBLOR (QLRI-2001-00015) and from the NIH grant R01 HGO2273. Swiss-Prot 
activities at the SIB are supported by the Swiss Federal Government 
through the Federal Office of Education and Science. PIR activities are 
also supported by the National Science Foundation (NSF) grants 
DBI-0138188 and ITR-0205470.

9. TERMS OF USE
UniProt is available for both commercial and non-commercial use. Please 
see http://www.uniprot.org/terms.shtml for details.

10. CITATION
If you want to cite UniProt in a publication please use the following 
reference:
Bairoch A., Apweiler R., Wu C.H., Barker W.C., Boeckmann B., Ferro S., 
Gasteiger
E., Huang H., Lopez R., Magrane M., Martin M.J., Natale D.A., O'Donovan C.,
Redaschi N., Yeh L.S. (2005) The Universal Protein Resource (UniProt). 
Nucleic
Acids Research 33:D154-D159 (2005).

11. CONTACT
EMBL Outstation
European Bioinformatics Institute (EBI)
Wellcome Trust Genome Campus
Hinxton
Cambridge CB10 1SD
United Kingdom
Telephone: (+44 1223) 494 444
Fax: (+44 1223) 494 468
Electronic mail address: datalib at ebi.ac.uk / swissprot at ebi.ac.uk
WWW server: http://www.ebi.ac.uk/

Swiss Institute of Bioinformatics (SIB)
Centre Medical Universitaire
1, rue Michel Servet
1211 Geneva 4
Switzerland
Telephone: (+41 22) 702 50 50
Fax: (+41 22) 702 58 58
Electronic mail address: swiss-prot at expasy.org
WWW server: http://www.expasy.org/

Protein Information Resource (PIR)
Georgetown University Medical Center
3900 Reservoir Road, NW
Box 571455
Washington, DC 20057-1455
United States of America
Telephone: (+1 202) 687 1039
Fax: (+1 202) 687 0057)
Electronic mail address: pirmail at georgetown.edu
WWW server: http://pir.georgetown.edu





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