In article <prm.131.000CB400 at aber.ac.uk> prm at aber.ac.uk (Pedro Mendes) writes:
>eanv20 at castle.ed.ac.uk (John Woods) wrote:
>>>Substance:
>>Kacser and Acerenza have recently published a `Universal method for
>>achieving increases in metabolite production' [Eur. J. Biochem.
>>216:361-367 (1993)]. So that's that, then. Better find a different
>> {stuff about [Form: deleted}
>>>And as it looks as if this is just a systematic application of the
>>branchpoint theorem,
Quite correct and understood by many of us involved in mca.
>I don't know where you recosigned the branch point theorem in this paper. If
>'branch point theorem' means 'the sum of the input fluxes is equal to the
>sum of the output fluxes', this is just a consequence of the definition of a
>steady state, it has nothing to do with control. Remember that this is about
>LARGE changes, therefore completely outside the scope of MCA
As an amateur - not by choice and virtually penniless in the process -
it makes me feel ill to find professionals who are paid good money plus
all research expenses paid for, making mistakes like this. The second
law at work yet again..... I know I should be constructive here, but all I
can say is read the literature.
>Pedro Mendes
>prm at aber.ac.uk>>
Herbert Sauro.
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