Abstract to CABIOS paper vol 9(4), p441-450 (1993)
SCAMP: a general-purpose simulator and metabolic control analysis
program. Herbert Sauro.
SCAMP is a general-purpose simulator of metabolic and chemical networks.
The program is written in C and is portable to all computer systems that
support an ANSI C compiler. SCAMP accepts metabolic models described in
a biochemical language, and this enables novice as well as experienced
users rapidly to build and simulate metabolic systems. The language is
sufficiently flexible to enable other types of model to be built, eg
chemostat or ecological models. The language offers many facilities,
including: the ability to describe metabolic pathways of any structure
and possessing any kinetics using normal chemical notation; optionally
build models directly from the differential equations; differing
compartment volumes; access to flux, concentration and rate of change
information; detection of conserved cycles; access to all coefficients
and elasticities of metabolic control analysis; user-defined forcing
functions at the model boundaries; user-defined monitoring functions;
user-configurable output of any quantity. From the model description
SCAMP can either generate C code for later compilation to produce fast
executable stand-alone models or run-time code for input to the run-time
interpreter for immediate execution. The simulator also incorporates an
inbuilt symbolic differentiator for evaluating the Jaobian and
elasticity matrices.
How to get it:
Available with full documentation for PCs from the Oxford ftp software
archive at bmsdarwin.brookes.ac.uk
Herbert Sauro
