Ubiquinone in plasma is usually measured by HPLC. You have to measure
both oxidised and reduceed forms. Amount is approx. 1ug/ml plasma.
Refs:
Liver 14:138-140
Anal Biochem 157:106-116
Chem Pharm Bull 27:1237-1244
J Chrom 430:11-19
J Chrom 425:87-89.
Few studies of plasma ubiquinone have been made in pathological
conditions although ubiquinone deficiency has been described (
Ogasahara S, Engel AG, Frens D, and Mack D. Muscle coenzyme Q deficiency
in familial mitochondrial encephalomyopathy. Proceedings of the National
Academy of Sciences of the United States of America 1989 Apr; 86:
2379-82.)
Hope this is helpful
Simon Eaton
