On 4 Nov 1995, Bart Bartholomew wrote:
> I was making a deposit at my local blood bank, when I asked the nurse
> about adapting to the 6200 foot altitude.
> She showed me a text that indicated that 2,3-dyphosphoglycerate levels
> affect oxygen transfer to the cells.
> The text did not show the precursors or regulatory agents for this
> chemical, although a chart did indicate that it was sensitive to the
> blood PH.
> Does anyone have information about this ?
> Bart Bartholomew hcbarth at rmii.com>>Hello Bart,
A good starting point will be an article by EW Westhead et al.1984
Control of oxygen delivery from the erythrocyte by modification of
pyruvate kinase. Current topics in cellular regulation, 24:21-34.
Hope this helps,
Claude
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