IUBio

Fatty acid activation?

Johann Joets joets at hermes.univ-poitiers.fr
Wed Nov 15 16:08:15 EST 1995


In article <48c7m2$b8 at news.fonorola.net>, Harvey Hawes <HAWESG at cia.com> says:
>
>Hi,
>
>Could anybody tell me the enzyme that "activates" a fatty acid. That is, 
>the enzyme that adds a SH-CoA group to a fatty acid so that it can 
>undergo beta-oxidation etc. Does an enzyme do this or is it a result of 
>an uncatalyzed thio-esterfication?
>
>Harvey
>

Dear Harvey,
The enzyme responsible for this is acyl-CoA synthetase ( energy from ATP is needed)

Johann
***********************************************************
Johann JOETS
Institut de Biologie Moleculaire et d'Ingenierie Genetique
Laboratoire de Genetique Physiologique et Moleculaire
Universite de Poitiers
40, Av du Recteur Pineau, 86 022 Poitiers
TEL : 49 45 38 64
FAX : 49 45 35 03
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