Although it does not contain a survey of experimental data, the following
paper might be interesting in the context of the S=Km assumption:
R. Heinrich and E. Hoffmann: Kinetic Parameters of Enzymatic Reactions in
States of Maximal Activity; An Evolutionary Approach. J. theor. Biol. 151
(1991) 249-283. It gives a theoretical explanation of why this matching of
substrate concentration and Michaelis constant is physiologically
advantageous in the sense of catalytic efficiency.
An interrelation between the S to Km matching and the usage of normalized
control coefficients was pointed out in
S. Schuster and R. Heinrich: The Definitions of Metabolic Control Analysis
Revisited. BioSystems 27 (1992) 1-15.
Stefan Schuster (Berlin)
