Reply:
This has been extensively studied.
For a review, see Max Perutz,
"Mechanism of Cooperativity and Allosteric Regulation in proteins"
Cambridge Univ. Press, 1989
Jerry
On 14 Feb 1996, 95 wrote:
> I'm looking for any works on the dynamics of Hb-O2 association
> and dissociation.
> As Staub has already shown (Staub, Velocity of O2 uptake by
> human red blood cells. J. Appl. Physiol. 16(1961) pp. 511-516
> the coefficient k' of the equation:
>> k'
> Hb + O2 ------------> HbO2
> <------------
> k
>> depends on the fraction of saturation of Hb (f). I'm looking for
> any other work relating to this and specially some numeric
> results ( k'(f) ).
>> please e-mail to banaei at citi2.fr or banaei at ibt.univ-angers.fr>> thanx in advance
>>> Dr. A. BANAEI
> Institut de Biologie Theorique
> Angers - France
>>http://www.ibt.univ-angers.fr>>
