IUBio

malonate metabolism

Leo klebs.bbs at bbs.life.nthu.edu.tw
Fri Mar 22 01:47:25 EST 1996


   Malonic acid is a well known competitive inhibitor of some
  enzymes in TCA cycle. The dicarboxylic acid is also known to exist
  in relative high concentrations in plants.  I am very interested
  in knowing why eating vegetables does not cause any unpleasant
  effects.  Is there any evidence showing that malonate can not get
  into cells ?  Or our intestine simply refuses absorption of this
  compound ?   Thanks  a lot for your response.

    Hwan-You Chang




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