you should contact Hans Werterhof (or Westerhoff) in Amsterdam (The
Netherlands). He's a world specialist in this field
In article (Dans l'article) <v02130500aea38cd8d20f@[137.187.142.99]>,
dsul at HELIX.NIH.GOV (Daniel M. Sullivan) wrote (écrivait) :
> I have only recently learned of metabolic control analysis but I find it
> very interesting. Being a pharmacologist by training I was wondering if
> anybody has considered signal transduction pathways as a special case of
> metabolic control. These pathways are very tightly controlled and capable
> of inducing massive changes in the concentration of a single metabolite.
> Can this be accomplished simply by regulating an enzyme with a control
> coefficient very close to 1, or is there more to the story. If not, is
> there something to be learned about more subtle changes in metabolic
> pathways by studying this relatively simple case. Any thoughts?
>> Daniel M. Sullivan, Ph.D.
> NEI/NIH - Lab of Immunology
> Section on Ocular Gene Therapy
> Bldg 10 Room 10N202
> 9000 Rockville Pk.
