In article <32fad9ab.65429341 at news.sun.ac.za>, Jannie Hofmeyr
<jhsh at maties.sun.ac.za> writes
>Dear Sammys and Marys
>< snipping reluctantly >
etc
>(and, of course, the theoretical development of the framework). Our
>paper aimed to give one such example: without any modelling whatsoever
>we could show with MCA that when a metabolite regulates its synthesis
>by direct product inhibition (as serine does in mammals), the only
>type of inhibition that would be effective is uncompetitive inhibition
>(the type with which serine inhibits phosphoserine phosphatase).
...but here's another, with just MCA and no numerical simulation in
sight, it is easy to how, why and when cascade structures display
extreme sensitivity to inputs. Now of course you could work out the same
answer doing numerical simulation but I bet it would take longer and you
wouldn't be half so enlighened.
>>merrily mary along.
>>Jannie
>>Herbert
--
Herbert M Sauro
email: HSauro at fssc.demon.co.uk
Telephone: 01974 282428
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"He who cannot draw on 3000 years is living from hand to mouth" Goethe
"Ah, but a man's reach should exceed his grasp, or what's a heaven for?"
R Browning.
