IUBio

Logarithmic definitions of control coefficients

David Fell daf at bms.brookes.ac.uk
Wed Jan 15 08:09:03 EST 1997


Hans Schepers wrote:

> To my biological viewpoint, only the fractional
> form is correct, since it does not make any sence 
> to take a logarithm (or any other transcendental function)
> of a non-dimensionless quantity.

In my view, this is a very weak argument.  Formally it may not be correct to 
take logarithms of quantities with dimensions, but of course it is very 
common shorthand in science, for example in thermodynamic and kinetics 
applications.  Any objection can be worked around by using quantities 
relative to some defined state (e.g. 1M for concentrations ...).   The 
difference about this normalisation is that the answer does not change 
depending on your choice of reference state for normalisation, unlike the 
fractional change form which does. Of course, this independence of the 
actual reference state chosen in the logarithmic version exactly illustrates 
why it is not very important to worry about converting to relative measures.

Would anyone seriously object to using a logarithmic plot to study an 
exponential growth of biomass on the grounds that you can't take logs of a mass?

David Fell

=========================================================

David Fell,
School of Biological & Molecular Sciences,
Oxford Brookes University,
Oxford OX3 0BP,           Tel. +44 (0)1865 483247
UK                        FAX  +44 (0)1865 484017

daf at bms.brookes.ac.uk

See my book at:  http://www.portlandpress.co.uk/books/isbn/185578047X.htm




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