IUBio

MCA & numerical analysis

Petr Kuzmic pkuzmic at biokin.com
Wed Sep 3 18:35:29 EST 1997


Michael Kohn wrote:

> David Garfinkel and I worked closely for over 10 years in developing
> highly detailed models of intermediary metabolism in heart and liver 
> (see the list of our publications in my Web pages at the URL below). 

I looked, but before I take the trip to the library to read ...

Garfinkel D, Kohn MC, Achs MJ, Phifer J, and Roman G-C. Construction of
more reliable complex metabolic models without repeated solution of
their constituent differential equations, Math Computers Simulation
1978; 20:18. 

...do you think the construction of complex metabolic models _without
solving differential equations_ could be summarized in a few words? 
What assumptions had to be made?  Is there a full text of this paper
posted somewhere?

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Petr Kuzmic, Ph.D.      |          (608) 256-4790
BioKin Consulting       |      fax (708) 256-1269
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