paradox of metabolic signals

[Athel Cornish-Bowden]

Kyn Wai Chung asked:

>I am trying to find information about the following:-
>- amplification of metabolic signals e.g. via allosteric enzymes,
>substrate cycles and enzymatically interconvertable forms of enzyme

There is a certain amount of information about the first two of these in
Chapter 9 of my book Fundamentals of Enzyme Kinetics
(http://ir2lcb.cnrs-mrs.fr/~athel/fek.htm), and about interconvertible
forms of enzymes in Chapter 10, which is available on the web at
http://ir2lcb.cnrs-mrs.fr/~athel/mcai.htm.

>- steady state versus changes in concentration

It's not clear to me what you mean by this.

>- signal molecules that aren't intermediates in pathways.

Nor this. Could you give some examples?

Athel

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