Dear colleagues,
Can we draw your attention to a detailed description of an
algorithm for detecting all elementary flux modes (pathways) in
biochemical reaction networks?
It is illustrated by a running example and can be downloaded as a PDF file
from
ftp://sodom.bioinf.mdc-berlin.de/pub/metabolic/metatool/algorithm.pdf
or http://bms-mudshark.brookes.ac.uk/algorithm.pdf
This protocol is easier to read (bigger print size) then the computational
protocol we published earlier in:
S. Schuster, D. Fell and T. Dandekar: A General Definition of
Metabolic Pathways Useful for Systematic Organization
and Analysis of Complex Metabolic Networks, Nature Biotechnol. 18 (2000)
326-332,
and, more importantly, the PDF file has also the formulas all printed right
(regrettably there are some typesetting errors left in equation (4), in
equation (7) and in line 3, p.332 in the computational protocol of the above
publication).
Kind regards,
Thomas Dandekar (Heidelberg)
David Fell (Oxford)
Stefan Schuster (Berlin)
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