The program DynaFit, free for academic researchers,
has been recently updated to version 3.24. This
version features more comprehensive output from
simultaneous analysis of multiple data sets (in
the "local analysis" mode).
The program is most useful in the analysis of complex
reaction mechanism, for which traditional (algebraic)
kinetic equations cannot be derived.
EXAMPLE: "TIGHT BINDING" INHIBITION OF AN ENZYME DIMER
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DYNAFIT INPUT
[mechanism]
Monomer + Monomer <==> Dimer : k1 k-1
Dimer + Inhibitor <==> Complex : k2 k-2
Dimer + Substrate <==> Intermediate : k3 k-3
Intermediate <==> Dimer + Product : k4 k-4
REFERENCES & LINKS
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Home page http://www.biokin.com/dynafit/
Download http://www.biokin.com/dynafit/download.html
User manual http://www.biokin.com/dynafit/scripting/
Reference P. Kuzmic (1996) Anal. Biochem. 237, 260-273.
Please contact me if you have any questions about
installing or running the program.
Best Regards,
- P.K.
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P e t r K u z m i c, Ph. D. * BioKin Ltd.
1652 S. Grand Ave. * Suite 337 * Pullman, WA 99163
509.334.4131 * 509.332.3493 fax * http://www.biokin.com
