IUBio

metabolic simulators

Ming Chen chen at iti.cs.uni-magdeburg.de
Tue Apr 10 03:52:06 EST 2001


Thank DynaFit. Unfortunately I cannot install it completely. When I run
DynaFit.exe, there is a error: "An error occurred during the move data
process: -623". Please tell me how to.
>From scripting document, every biochemical reaction in DynaFit should has
data of substrates and products
concentration and kinetic values, such as K and V...? so how to deal with it
that the whole reactions take place at the same time (parallel processes).
It seems Gepasi and Jarnac have no such problem as they regard reaction
network as a black-box?

Petr Kuzmic wrote:

> Ming Chen wrote:
>
> > What else tools can be used to model and simulate biochemical reaction
> > network except E-Cell, Gepsi...? Some DOS version tools seem to be out
> > of date already.
>
> The program DynaFit [P. Kuzmic (1996) Anal. Biochem. 237,
> 260-273] is useful in the analysis of complex reaction
> mechanism, for which traditional (algebraic) kinetic
> equations cannot be derived.  In my opinion, the program's
> utility in the simulation of biochemical reaction networks
> has not been fully explored by workers in that area.
>
> Attached below is a bibliography containing 54 journal
> articles that cited DynaFit over the last three years. Most
> citations are from articles in the journal Biochemistry,
> followed by the Journal of Biological Chemistry, and
> Biochimica & Biophysica Acta.
>
> The main application of DynaFit seems to be in figuring out
> biochemical reaction mechanisms from kinetic and/or
> equilibrium data.  However, the program has been used in
> many different areas, such as environmental chemistry, food
> chemistry, guest-host interactions, and structure-activity
> studies.
>
> The program is available free of charge to academic
> researchers:
>
> Home page:   http://www.biokin.com/dynafit/
> Download:    http://www.biokin.com/dynafit/download.html
> User manual: http://www.biokin.com/dynafit/scripting/
>
> Please contact me if you have any questions about installing
> or running the program.
>
> Best Regards,
>
>     - P.K.
>
> -------------------------------------------------------
> P e t r   K u z m i c,  Ph. D.  * BioKin Ltd.
> 1652 S. Grand Ave. * Suite 337  * Pullman, WA 99163
> 509.334.4131 * 509.332.3493 fax * http://www.biokin.com
>




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