C.elegans lysosome question

Kay Hofmann khofmann at isrec-sun1.unil.ch
Wed Apr 26 20:00:34 EST 1995


Dear C.elegans specialists,

I would like to know if C.elegans cells contain lysosomes that
are analog to the lysosomes of vertebrate cells.
To be more specific, should I expect the usual set of lysosomal enzymes
(cathepsins, acid phosphatase, acid lipases etc.) in C.elegans lysosomes?

A search in the literature database did not give too much useful information
on this topic, searching the dna/protein databases revealed some proteins
with homology to mammalian lysosomal enzymes but I am not sure if these
proteins are really located in the lysosomes in the worm.

Any information would be appreciated

Kay




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