increased permeability mutants

[Eric C. Anderson]

In article <v0151010eab7173a6db6f@[143.48.7.204]>, hengartn at CSHL.ORG
(Michael Hengartner) wrote:

> Dear nema-netters,
> 
> There have been anecdotal reports every now and then that some mutants show
> increased sensitivity to lots of different drugs, presumably because they
> have an increased cuticular permeability.  What's the latest on this?  Are
> these anecdotal observation bogus?  Published?  Does anybody have a
> compendium of which mutants show increase sensitivity?  Any information on
> this topic would be greatly appreciated.

i have a related question...would these mutants (if they truly exist) be
better candidates for immunocytochemistry other similar experiments because
of their increased cuticular permeability than are N2 worms?

thanks,
eric

-- 
**************************************************
*science never gets boring...                    *
*it's not a job, it's a sandbox.                 *
*                       -unknown NIH immunologist*
*                        on NPR, 2/12/95         *
**************************************************
eric c. anderson                                
anderson at pharmdec.wustl.edu
dept. of molecular bio. and pharm.               (314)362-3963 (lab)
washington univ. school of medicine              (314)862-2435 (home)
660 s. euclid box 8103                           (314)362-7058 (FAX)
st. louis, mo 63110