splicing in UTR's

Joe Chou jchou at cgl.ucsf.edu
Fri Jul 19 19:19:58 EST 1996


hobert at FRODO.MGH.HARVARD.EDU (Oliver Hobert) writes:

>Hi folks - Does anybody have an overview and/or own experience about if/how
>likely it is that splicing occurs in 5' or 3' UTR's of C.elegans genes ?
>That is, if you have localised a genes first/last exon in the genomic
>sequence, is the genomic sequence before/after the first/last exon the
>5'/3'-UTR on the mRNA or might there be additional introns ?
>Thanks,
>Oliver

The gene I cloned, odr-2, has an intron in the 5' untranslated region,
upstream of the only available start ATG's.

Not exactly a sweeping review of the possibility of 5' or 3' UTR
introns, but it's one case *I* know of :)

Joe Chou
  (Cori Bargmann's lab at UCSF)
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