concept of "pattern"?

Raul Valdes-Perez valdes+ at CS.CMU.EDU
Mon Dec 19 18:53:58 EST 1994

Greetings, I am a computer scientist trying to develop systematic methods to 
detect subtle or complex patterns in cell biological data. 

For example, let's say that one has a time series image of a cell undergoing
division, in which the concentration of some protein activation ion is measured
through fluorescence-ratio imaging.  Let's also say that the ion is
hypothetically implicated in cell division.  After obtaining the data, the 
question becomes: is there a pattern in the images, or is it all just "random"?

I have been working on methods for this and similar problems, but would like to 
relate my approach to classical (or modern!) writers on the role and meaning
of the concept of "pattern" in cell biology.  I am familiar with the concept
of pattern in developmental biology, in which "pattern" is the body plan
(collections of fated cells), but there the concept is more static and narrow,
I suspect.

So, here's my question:  what author has written penetratingly on what it means
to look for patterns in cell biology, on what a pattern is, on why one would
like to find patterns in the first place, and so on?


Raul E. Valdes-Perez	        Research Computer Scientist
Computer Science Department &	
Center for Light Microscope     email: valdes at
  Imaging and Biotechnology     tel: (412) 268-7127
Carnegie Mellon University	fax: (412) 268-5575
Pittsburgh, PA 15213 - USA	

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