Mastoparan activation of G proteins and NDPK.

Matthew W Martin ucgbmwm at ucl.ac.uk
Mon Feb 21 14:10:25 EST 1994


 Mastoparan, a component of wasp venom, has been shown to activate
the heterotrimeric GTP-binding protein (G protein), Go - and other
G proteins (Higashijima, et al; 1988; J. Biol. Chem.; 263; 6491-6494).

 Does anyone know if there is any evidence (published or not) about
the effect of this peptide on monomeric GTP-binding proteins?

 I'd like to get a discussion started here about how this peptide 
activates G proteins. Afterall, isn't a good discussion the TRUE
PURPOSE of News Groups?

    Matthew W Martin.




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