Commercial supplier for CSF-1?

Gerry Feldman feldman at a1.cber.fda.gov
Thu Jul 28 12:54:01 EST 1994


In article <9407201205.AA30961 at polywog.biology.uofs.edu>,
GREUELB1 at JAGUAR.UOFS.EDU (Brian T. Greuel) wrote:

> Does anyone know of a commercial supplier for colony stimulating factor-1 
> (CSF-1; i.e. the ligand for the receptor encoded by the fms oncogene)?  Is it 
> going by another name these days?
> 
> What is the difference between CSF-1 and the following factors:  G-CSF, GM-
> CSF, and M-CSF?
> 
> Thanks for any information you can provide.
> 
> Brian Greuel
> greuelb1 at jaguar.uofs.edu

Why pay for it? L-929 cells produce copious amounts of M-CSF (a 1-5%
solution of conditioned media is sufficient to induce macrophage
differentiation). However, if you need the pure/recombinant stuff, both
Sigma and Genzyme sell it, as does R & D. I think Gibco-BRL might as well.

Gerry Feldman



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