T-antigen binding sites in mammalian genome

mhollowa at epo.som.sunysb.edu mhollowa at epo.som.sunysb.edu
Thu Jun 16 21:24:17 EST 1994


Can anyone tell me if any good work has been done to explain 
the function of SV-40 large T-antigen binding sites in the 
genome.  Are they just randomly distributed or does the SV40 
protein take advantage of a cellular protein's binding site?  
The organism doesn't maintain the site so that SV40 can 
transform the cells.  It should have some cellular function, no?

Mike Holloway
mhollowa at epo.som.sunysb.edu




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