Does HIV kill cells?

Matthew P Wiener weemba at sagi.wistar.upenn.edu
Thu Mar 24 15:04:10 EST 1994


In article <2msg2u$ste at s.ms.uky.edu>, mpm at seqanal (Mark Mattson) writes:
>With respect to HIV itself, I think it is clear that the virus can
>kill neurons in the CNS, apparently by stimulating an influx of
>calcium.  It is not clear (to me, anyway) whether this phenomenon
>involves killing of uninfected neurons by extracellular holovirus or
>whether it's only infected cells that die.

HIV does not, apparently, infect neurons.  It infects microglia, and
causes them to join together.
-- 
-Matthew P Wiener (weemba at sagi.wistar.upenn.edu)



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