chromatin condensation and cleavage

Mon Aug 14 09:13:16 EST 1995

cleavage to large fragments (50-200 kD) probably occurs before
cleavage to ladder sizes--Sikorska & Walker, Biochem. Cell Biol.
1994, released ca Feb, 1995--and the condensation can occur
before distinct ladders are seen--Oberhammer, Sikorska, & others,
ca 2 years ago.  There have been a couple of very recent papers
on the condensation, but it is certainly not a chromosome-by-
chromosome condensation as in mitosis.
Richard A. Lockshin/Dept. Biol. Sci. St. John's U. 8000 Utopia Pkwy
Jamaica NY 11439 USA/Phone 718: 990-1854/ Fax 718: 380-8543
[email address may change soon]
In article <40ld4r$fio at> lhe at (Lihua He) writes:
>Dear Netters:
>We had a vote on the following question in a group meeting and we got a tie, so
>could you please help us.
>The question is: does chromatin cleavage occur earlier or later than chromatin
>condensation during apoptosis?
>Is there any difference between chromatin condensation of an apoptotic cell and
>of a normal cell cycle?
>Lihua He
>University of Houston

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