G-proteins

AJ. Collier Adam.Collier at bristol.ac.uk
Wed Jan 18 10:07:45 EST 1995


Is there anyone working on establishing whether a particular receptor 
utilizes a heterotrimeric G-protein as part of its signal transduction 
cascade. At the moment I am attempting to permeablize an epithelial cell 
line with streptolysin-O, allowing the entry of GTP analogues into the 
cell to see what effect this might have on signal transduction.

Also, is there such a thing as a G-protein-linked receptor which DOESN'T 
have 7 membrane spanning regions???????

Thanx in advance

		Adam




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