Good example of second messengers?

Rick Neubig RNeubig at
Tue Jan 31 10:35:03 EST 1995

mbxfd at (Fergus Doherty) wrote:
> I need to find some good examples of intracellular second messenger
> systems, for both the cAMP/PKA system and the Phoshoinositide/Ca/PKC
> system. What I need are pointers to publications, preferably reviews, that
> describe such a system in a particular cell type, from receptor binding to
> final effect, complete. 

You might want to look at a book by Jennifer Linderman here at the
University of Michigan in Chemical Engineering. She (and her co-author)
have attempted to look at a quantitative treatment of signal transduction
responses from beginning to end.

Title:          Receptors : models for binding, trafficking, and signaling /
                   Douglas A. Lauffenburger, Jennifer J. Linderman.
 Published:      New York : Oxford University Press, 1993.
 Description:    x, 365 p. : ill. ; 25 cm.
 SUBJECT HEADINGS (Library of Congress; use s=):
                 Cellular signal transduction.
                 Cell receptors.

Rick Neubig

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