A549 lung alveolar carcinoma

Denis LeBel dlebel at COURRIER.USHERB.CA
Thu Jul 6 15:35:55 EST 1995


Hi there!
I am thinking of using the human lung alveolar carcinoma A549 cell line in
secretion studies. Does anyone familiar with this cell line, could tell me
if it is easy to measure stimulated secretion of PC, PS, surfactant
proteins, or any secretory product from these cells in culture? Is the
response to secretagogues significant enough to be easily discriminated from
the basal constitutive secretion? Is the basal, unstimulated secretion, very
important?
Thanks very much for any information or references on the A549 cell line.
Dr. Denis LeBel,
Departement de Biologie,
Universite de Sherbrooke,
Sherbrooke, QC,
CANADA, J1K 2R1

Tel. (819)821-7075
FAX. (819)821-8049




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