DHFR substrates that can be crosslinked?

Mark N. Mayhew mmayhew at nyc.pipeline.com
Mon Mar 27 17:57:42 EST 1995

I was wondering whether any substrates or inhibitors of dihydrofolate
reductase had been developed that could be specifically cross-linked to
DHFR once bound. Any information on this would be greatly appretiated. 
Many Thanks, 

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