Protease Inhibitors

Cornelius Krasel krasel at
Mon Oct 30 17:55:36 EST 1995

Tomas Bratt (tomas.bratt at wrote:
> In article <46kbrd$76v at>,
> <andrew at> wrote:

> > Does anyone know of a protease inhibitor which might inhibit a protease 
> > which is cleaving at a pair of basic residues. ie -Arg-Arg-.

> Serin proteases, as pc3 or furin, cleave at Arg-Arg and are inhibited by
> EDTA among others. 

I thought EDTA would inhibit Metalloproteases -- why should it inhibit
Serin proteases?


/* Cornelius Krasel, U Wuerzburg, Dept. of Pharmacology, Versbacher Str. 9 */
/* D-97078 Wuerzburg, Germany   email: phak004 at  SP3 */
/* "Science is the game we play with God to find out what His rules are."  */

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