Protease Inhibitors

Cornelius Krasel krasel at wpxx02.toxi.uni-wuerzburg.de
Mon Oct 30 17:55:36 EST 1995


Tomas Bratt (tomas.bratt at medkem.lu.se) wrote:
> In article <46kbrd$76v at harbinger.cc.monash.edu.au>,
> <andrew at cobra.path.monash.edu.au> wrote:

> > Does anyone know of a protease inhibitor which might inhibit a protease 
> > which is cleaving at a pair of basic residues. ie -Arg-Arg-.

> Serin proteases, as pc3 or furin, cleave at Arg-Arg and are inhibited by
> EDTA among others. 

I thought EDTA would inhibit Metalloproteases -- why should it inhibit
Serin proteases?

Clueless,
--Cornelius.

--
/* Cornelius Krasel, U Wuerzburg, Dept. of Pharmacology, Versbacher Str. 9 */
/* D-97078 Wuerzburg, Germany   email: phak004 at rzbox.uni-wuerzburg.de  SP3 */
/* "Science is the game we play with God to find out what His rules are."  */



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