enzymes and activation energy?

[Chris Purple]

isnt this a mechanism for the decrease in the Ea?

On 25 Sep 1995, Paul. S. Brookes. wrote:

> rray at ix.netcom.com (ROMAN RAY ) wrote:-
> 
> >How does an enzyme lower the activation energy of a reaction and
> >therefore causing the catalysis of the reaction????
> 
> I thought enzymes catalysed by stabilising the transition state of a
> reaction (presumably by transiently bonding/interacting with it)
> 
> This can be proven by taking a proposed transition state analogue for a
> given reaction, and making an antibody to it.  The antibody should then act
> as a catalyst for the original reaction.  This has been done with limited
> success.
> 
> Regards,
> PSB
> 
> 
> ------------------------------
> Paul Brookes >><< psb at bioc.cam.ac.uk >><< 01223 333649
> Biochemistry, Tennis Court Rd, Cambridge, CB2 1QW, UK.
> http://www.bio.cam.ac.uk/lab/brand/people/paul/paul.html
> 
> 
> 
> 
>