tyrosine kinase inhibitors

David Ward Rusnak rusnak~dw at glaxo.com
Thu Apr 18 09:19:47 EST 1996


In article <4l33nb$fhp at fu-berlin.de>, saihtam at chemie.fu-berlin.de (Mathias
Dreger) wrote:

> Hello there,
> Does anybody know an inhibitor of protein tyrosine kinases that is capable of 
> entering cultured non-permeabilized cells ?
> 
> Thanks in advance
> 
> Mathias

Herbamycin also.

Along with Genestein, Tyrphostin's (available from Boerhinger, I think)
you can get varying levels of specificity for particular tyrosine kinases
(but probably not absolute specificity for any one TK)

Later,

Rusnak



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